Search among available cruises
Filter Cruises
Home›Destinations›South America

Departure calendar South America

Have you already decided when will be your next cruise with destination South America? Whatever month you choose will be the perfect opportunity to set off to discover the local wonders

  • 2025
  • 2026
  • 2027
May 2025 June 2025 July 2025 August 2025 September 2025 October 2025 November 2025 December 2025
January 2026 February 2026 March 2026 April 2026 May 2026 June 2026 July 2026 August 2026 September 2026 October 2026 November 2026 December 2026
January 2027 February 2027 March 2027 April 2027 May 2027 June 2027 July 2027 August 2027 September 2027 October 2027 November 2027 December 2027

Cruises South America

612 cruises

South America: Brazil

Rio de Janeiro Itinerary South America
from $1,452
price per person Taxes included
See the cruise Book Online Book Online
MSC Lirica | 8 Jan 2026
Duration: 7 nights
Departure from: Rio de Janeiro Landing: Rio de Janeiro
Itinerary:
1. Rio de Janeiro,
2. Buzios,
3. navigation,
4. Itajai,
5. Santos,
6. Ilhabela,
7. Ilha Grande,
8. Rio de Janeiro

South America: United States, Mexico, Honduras, Belize, Bahamas, Puerto Rico, Dominican Republic, Turks and Caicos

Fort Lauderdale Itinerary South America
from $4,213
price per person Taxes included
See the cruise Book Online Book Online
Enchanted Princess | 21 Jun 2025
Duration: 14 nights
Departure from: Fort Lauderdale Landing: Fort Lauderdale
Itinerary:
1. Fort Lauderdale,
2. navigation,
3. Cozumel Island,
4. Roatan,
5. Belize City,
6. navigation,
7. navigation,
8. Fort Lauderdale,
9. Princess Cays,
10. navigation,
11. San Juan,
12. Amber Cove,
13. Grand Turk,
14. navigation,
15. Fort Lauderdale
sold out

Argentina, Brazil, Uruguay

Buenos Aires Itinerary South America
from $1,306
price per person Taxes included
MSC Preziosa | 12 Mar 2026
Duration: 7 nights
Departure from: Buenos Aires Landing: Buenos Aires
Itinerary:
1. Buenos Aires,
2. navigation,
3. navigation,
4. Santos,
5. Camboriú,
6. navigation,
7. Punta Del Este,
8. Buenos Aires

South America: Brazil

Maceio Itinerary South America
from $1,489
price per person Taxes included
See the cruise Book Online Book Online
MSC Armonia | 17 Feb 2026
Duration: 7 nights
Departure from: Maceio Landing: Maceio
Itinerary:
1. Maceio,
2. Salvador,
3. Ilheus,
4. navigation,
5. Rio de Janeiro,
6. navigation,
7. navigation,
8. Maceio

South America: Ecuador

Puerto Baquerizo Moreno Itinerary South America
from $26,333
price per person Taxes included
See the cruise Book Online Book Online
Silver Origin | 28 Jun 2025
Duration: 7 nights
Departure from: Puerto Baquerizo Moreno Landing: Puerto Baquerizo Moreno
Itinerary:
1. Puerto Baquerizo Moreno,
2. Kicker Rock,
3. Bartolome Island,
4. Santiago Island,
5. Punta Vicente Roca,
6. navigation,
7. Punta Espinoza,
8. Caleta Tagus,
9. Elizabeth Bay,
10. Isla Floreana,
10. Bahia Post Office,
13. Santa Cruz Island,
14. Puerto Ayora,
15. Dragon Hill,
16. Isla Guy Fawkes,
17. navigation,
18. Puerto Baquerizo Moreno

South America: Brazil

Itajai Itinerary South America
from $1,004
price per person Taxes included
See the cruise Book Online Book Online
Costa Diadema | 4 Apr 2026
Duration: 4 nights
Departure from: Itajai Landing: Itajai
Itinerary:
1. Itajai,
2. Santos,
3. Ilhabela,
4. navigation,
5. Itajai

South America: Ecuador

Puerto Baquerizo Moreno Itinerary South America
from $28,344
price per person Taxes included
See the cruise Book Online Book Online
Silver Origin | 14 Feb 2026
Duration: 7 nights
Departure from: Puerto Baquerizo Moreno Landing: Puerto Baquerizo Moreno
Itinerary:
1. Puerto Baquerizo Moreno,
2. Kicker Rock,
3. El Barranco,
4. Bahia Darwin,
5. North Seymour Island,
6. Sullivan Bay,
7. navigation,
9. Punta Moreno,
10. Santa Cruz Island,
11. Puerto Ayora,
12. Gardner Bay,
13. Punta Suarez,
14. Isla Lobos,
15. Puerto Baquerizo Moreno,
16. Puerto Baquerizo Moreno

South America: Brazil, Cape Verde, Spain, Morocco, Portugal

Santos Itinerary South America
from $2,796
price per person Taxes included
See the cruise Book Online Book Online
Costa Diadema | 19 Apr 2026
Duration: 17 nights
Departure from: Santos Landing: Lisbon
Itinerary:
1. Santos,
2. Rio de Janeiro,
3. navigation,
4. navigation,
5. Salvador,
6. Maceio,
7. navigation,
8. navigation,
9. navigation,
10. navigation,
11. Praia,
12. navigation,
13. navigation,
14. Santa Cruz de Tenerife,
15. navigation,
16. Casablanca,
17. Cadiz,
18. Lisbon

South America: Italy, France, Spain, Portugal, Cape Verde, Brazil

Genoa Itinerary South America
from $3,052
price per person Taxes included
See the cruise Book Online Book Online
Costa Favolosa | 2 Nov 2025
Duration: 20 nights
Departure from: Genoa Landing: Rio de Janeiro
Itinerary:
1. Genoa,
2. Marseille,
3. Barcelona,
4. navigation,
5. Cadiz,
6. Lisbon,
7. navigation,
8. Funchal,
9. Santa Cruz de Tenerife,
10. navigation,
11. navigation,
12. Praia,
13. navigation,
14. navigation,
15. navigation,
16. navigation,
17. Recife,
18. Maceio,
19. Salvador,
20. navigation,
21. Rio de Janeiro

South America: Ecuador

Baltra Itinerary South America
from $14,589
price per person Taxes included
See the cruise Book Online Book Online
Celebrity Flora | 22 Jun 2025
Duration: 7 nights
Departure from: Baltra Landing: Baltra
Itinerary:
1. Baltra,
2. Puerto Egas,
3. Rabida,
4. Elizabeth Bay,
5. Caleta Tagus,
6. Sullivan Bay,
7. Bartolome Island,
8. Las Bachas,
9. Daphne Island,
10. North Seymour Island,
11. Puerto Baquerizo Moreno,
12. Punta Pitt,
13. Puerto Ayora,
14. Baltra
612 cruises

Reviews South America

13 reviews with average 7.62

Discover the impressions and ratings of other cruisers about cruises South America. Evaluate the experiences of others and make the right choice

star star star star 8/10

Roberto Greco Saturday, 30 December 2023
star star star star star 10/10

Giovanni Emanuele Fernandez Thursday, 28 December 2023
star star star star 7/10

Vincenzo Pascolo Monday, 10 April 2023
star star star star 8/10

Vito Fernando Gautieri Friday, 10 February 2023
star 1/10

vittorio Wednesday, 8 February 2023
star star 4/10

Stefania Bonfante Tuesday, 7 February 2023
star star star star star 10/10

Angela Donati Saturday, 21 January 2023
star star star star 8/10

Stefano Dionisi Thursday, 12 January 2023
star 1/10

Agatino Massimo Ventimiglia Tuesday, 10 January 2023
star 1/10

Giovanni Paternò Wednesday, 14 December 2022

Ports of departure South America

Get ready to experience your sea holiday with destination South America aboard the best cruise ships operating from the main ports of the region

  • South America: Featured ports
  • Other ports
Baltra Images of Baltra Barcelona Images of Barcelona Bridgetown Images of Bridgetown Buenos Aires Images of Buenos Aires Colon Images of Colon Fort Lauderdale Images of Fort Lauderdale Genoa Images of Genoa Halifax Images of Halifax
Itajai King George Island Los Angeles Maceio Miami Montevideo New York Puerto Baquerizo Moreno Puerto Williams Rio de Janeiro Salvador San Antonio Santiago Santos Southampton Valparaiso

South America: the ships

Get ready to experience your sea holiday aboard the best cruise ships operating from the main ports of the South America area

  • South America: Featured ships
  • Other ships
MSC Armonia Images of MSC Armonia MSC Fantasia Images of MSC Fantasia MSC Lirica Images of MSC Lirica MSC Preziosa Images of MSC Preziosa MSC Seaview Images of MSC Seaview Costa Diadema Images of Costa Diadema Costa Favolosa Images of Costa Favolosa Jewel Of The Seas Images of Jewel Of The Seas
Serenade Of The Seas Norwegian Jade Celebrity Equinox Celebrity Flora Oosterdam Volendam Enchanted Princess Sapphire Princess Sun Princess Queen Anne Azamara Journey Azamara Quest Silver Cloud Silver Endeavour Silver Nova Silver Origin Silver Wind Insignia Marina Vista Seabourn Venture Seven Seas Grandeur Seven Seas Mariner Seven Seas Splendor

South America: The countries to visit

Immerse yourself fully in the local culture and get ready to discover the wonders and gastronomy of the destination South America, one of the most loved and visited in the world.

  • South America: Countries highlighted
  • Other nations
Argentina Images of Argentina Brazil Images of Brazil Ecuador Images of Ecuador United Kingdom Images of United Kingdom Uruguay Images of Uruguay