Departure calendar San Diego

Browse the catalog of all cruises departing from San Diego now and find the one that suits your needs best.

Cruises from San Diego

63 cruises

Central America: United States, Mexico, Guatemala, Nicaragua, Costa Rica, Colombia, Cayman Islands

San Diego Itinerary Central America
from $5,214
price per person Taxes included
Insignia | Jul 3, 2025
Duration: 20 nights
Departure from: San Diego Landing: New York
Itinerary:
1. San Diego,
2. navigation,
3. navigation,
4. Cabo San Lucas,
5. navigation,
6. Zihuatanejo,
7. navigation,
8. Puerto Quetzal,
9. Corinto,
10. Puntarenas,
11. navigation,
12. navigation,
13. Cartagena De Indias,
14. navigation,
15. George Town,
16. navigation,
17. Miami,
18. Port Canaveral,
19. navigation,
20. New York,
21. New York

Central America: United States, Mexico, Costa Rica, Colombia

San Diego Itinerary Central America
from $1,730
price per person Taxes included
Serenade Of The Seas | Sep 19, 2025
Duration: 13 nights
Departure from: San Diego Landing: Miami
Itinerary:
1. San Diego,
2. navigation,
3. navigation,
4. Puerto Vallarta,
5. navigation,
6. Huatulco,
7. navigation,
8. Puntarenas,
9. navigation,
10. navigation,
11. Cartagena De Indias,
12. navigation,
13. navigation,
14. Miami

Central America: United States, Mexico, Guatemala, Costa Rica, Panama, Colombia, Cayman Islands

San Diego Itinerary Central America
from $3,061
price per person Taxes included
Radiance Of The Seas | Oct 4, 2025
Duration: 16 nights
Departure from: San Diego Landing: Fort Lauderdale
Itinerary:
1. San Diego,
2. navigation,
3. Cabo San Lucas,
4. Mazatlan,
5. navigation,
6. navigation,
7. Puerto Quetzal,
8. navigation,
9. Puntarenas,
10. navigation,
11. navigation,
12. Colon,
13. Cartagena De Indias,
14. navigation,
15. George Town,
16. navigation,
17. Fort Lauderdale

Central America: United States, Mexico

San Diego Itinerary Central America
from $933
price per person Taxes included
Norwegian Jade | Oct 18, 2025
Duration: 8 nights
Departure from: San Diego Landing: San Diego
Itinerary:
1. San Diego,
2. navigation,
3. Cabo San Lucas,
4. Mazatlan,
5. Puerto Vallarta,
6. navigation,
7. navigation,
8. San Diego

Central America: United States, Mexico

San Diego Itinerary Central America
from $777
price per person Taxes included
Norwegian Jade | Oct 26, 2025
Duration: 7 nights
Departure from: San Diego Landing: San Diego
Itinerary:
1. San Diego,
2. navigation,
3. Cabo San Lucas,
4. Mazatlan,
5. Puerto Vallarta,
6. navigation,
7. navigation,
8. San Diego
63 cruises

San Diego: A Historical Mosaic

San Diego, known as the birthplace of California, is steeped in rich history, from its early Native American roots to its founding by Spanish missionaries in 1769. The city has evolved from a humble mission into a bustling metropolis, all while preserving its historical charm, evident in the preserved Spanish architecture of Old Town San Diego State Historic Park. This area, along with the Cabrillo National Monument, offers a glimpse into the city's past, showcasing the diverse cultures that have shaped San Diego into the vibrant city it is today.

The Alluring Climate of San Diego

San Diego's climate is arguably one of its most attractive features, boasting year-round sunshine and mild temperatures. This idyllic weather facilitates an outdoor lifestyle, encouraging visitors to explore the city's expansive beaches, lush parks, and scenic walking paths. Whether you're sunbathing at La Jolla Cove, hiking in Torrey Pines State Natural Reserve, or enjoying waterfront dining, San Diego's climate makes every activity more enjoyable, earning it the title of "America's Finest City."

Discovering San Diego's Attractions

San Diego's attractions cater to every interest, making it a versatile destination for all types of travelers. The world-renowned San Diego Zoo and Safari Park offer up-close animal encounters, while Balboa Park houses museums, gardens, and the iconic California Tower. For maritime enthusiasts, the USS Midway Museum and the Maritime Museum of San Diego provide insight into naval history. San Diego's proximity to the Mexican border also introduces a unique cultural blend, enriching the city's already diverse array of attractions and activities.

A Taste of San Diego's Culinary Delights

The culinary scene in San Diego is as vibrant and varied as its landscape, with an emphasis on fresh, local ingredients and seafood. The city is renowned for its fish tacos, a local delicacy that reflects its coastal and Mexican influences. Craft beer enthusiasts will also find a haven here, as San Diego boasts one of the most dynamic craft beer scenes in the country. From upscale dining in the Gaslamp Quarter to casual beachside eateries, San Diego offers a culinary adventure for every palate.

Embarking on a Cruise from San Diego

For those looking to explore beyond the city, San Diego serves as an ideal departure point for cruises. The city's cruise terminal, located downtown near the vibrant Embarcadero, offers voyages to the Mexican Riviera, Hawaii, and the Panama Canal. Starting your cruise in San Diego not only provides an opportunity to enjoy the city's many attractions but also offers a seamless transition to the relaxation and adventure of a cruise vacation. With its stunning scenery, rich history, and welcoming climate, San Diego is the perfect port of call for cruisers seeking a memorable start to their journey.

All ships departing from San Diego

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