MSC Cruises Central America: 18 nights from Miami with MSC Poesia
Apr 23, 2026
United States, Colombia, Panama, Costa Rica, Mexico
Cruise itinerary
Departure Port: Miami ➞
Landing: Seattle
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Thursday, April 23, 2026 - 6:00 PMMiami
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Friday, April 24, 2026Navigation
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Saturday, April 25, 2026Navigation
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Sunday, April 26, 2026 7:00 AM - 5:00 PMCartagena De Indias
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Monday, April 27, 2026 9:00 AM - 7:00 PMColon
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Tuesday, April 28, 2026 9:00 AM - 9:15 AMPanama Canal
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Wednesday, April 29, 2026Navigation
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Thursday, April 30, 2026 7:00 AM - 5:00 PMPuntarenas
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Friday, May 1, 2026Navigation
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Saturday, May 2, 2026Navigation
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Sunday, May 3, 2026Navigation
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Monday, May 4, 2026 8:00 AM - 3:00 PMCabo San Lucas
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Tuesday, May 5, 2026Navigation
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Wednesday, May 6, 2026 7:00 AM - 8:00 PMSan Diego
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Thursday, May 7, 2026 8:00 AM - 8:00 PMLos Angeles
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Friday, May 8, 2026Navigation
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Saturday, May 9, 2026Navigation
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Sunday, May 10, 2026Navigation
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Monday, May 11, 2026 7:00 AMSeattle

Miami
Cruises departing from Miami: itineraries and offers!Miami is the most important city in Florida and is the ideal departure port for a Caribbean cruise. This city, founded at the end of the 1800s, is cosmopolitan and ready to welcome tourists with maximum comfort. Every day ships from the best companies set sail from Miami with itineraries ranging from 3 to 21 nights: discover all the cruises from Miami on our website and book your next vacation at unbeatable prices!
A Glimpse into Miami's Rich HistoryMiami, a vibrant city known for its dynamic culture and scenic beauty, holds a rich tapestry of history that dates back centuries. Initially inhabited by the Tequesta Native Americans and later claimed by Spain, Miami has transformed from a mangrove swamp into a bustling metropolis. The city's strategic location made it a crucial hub for trade and migration, contributing to its diverse cultural heritage. This fascinating blend of influences is evident in its architecture, traditions, and vibrant communities, making Miami a unique American city with a story to tell at every corner.
The Alluring Climate of MiamiMiami's climate is a major draw for visitors from around the globe. With warm, sunny weather year-round, it offers an eternal summer that appeals to sun-seekers and adventurers alike. The city enjoys a tropical monsoon climate, featuring hot, humid summers and warm, dry winters. This delightful weather allows for a plethora of outdoor activities, from sunbathing on its world-renowned beaches to exploring its lush, tropical landscapes. Miami's inviting climate makes it an ideal destination wishing to escape colder regions, promising a warm welcome in any season.
Must-Visit Attractions and SitesMiami is a treasure trove of attractions, catering to every interest. South Beach, known for its stunning Art Deco architecture and vibrant nightlife, is a must-visit. Art enthusiasts will revel in the colorful street art of Wynwood Walls, while history buffs can explore the ancient Spanish Monastery. For a taste of nature, the Everglades National Park offers thrilling airboat tours. Additionally, Miami serves as a gateway to the Bahamas and the Caribbean, making it a perfect starting point for cruises.
Savoring Miami's Local CuisineThe culinary scene in Miami is as diverse as its population, offering a fusion of flavors from around the world. Cuban influence is paramount, with local staples such as Cubano sandwiches and cafecito. Seafood lovers will delight in the fresh catches available, highlighted in dishes like ceviche and stone crab claws. The city's vibrant food scene is a reflection of its multicultural makeup, offering an adventure for the palate and an essential aspect of the Miami experience.
Embark on a Journey from MiamiFor those enchanted by the allure of the sea, Miami is not just a destination but a beginning. This city, with its state-of-the-art cruise terminals, is a premier starting point for voyages across the Caribbean, Mexico, and beyond. Embracing Miami's eclectic spirit, vibrant culture, and scenic beauty can only be matched by the adventures that await on a cruise originating from this dynamic city. With exclusive deals and packages available, there's no better time to embark on a journey that begins in Miami, promising an unforgettable experience on the high seas.

Cartagena De Indias
The City is a fairytale of romanticism, legends and pure beauty. Cartagena de Indias is an exciting place you will fall in love with.
The city was one of the first sanctuaries of African slaves freed in the America and is today populated by an ethnic melting pot of Colombian varieties. It is a vivid city, the ideal place if you are looking for something different from the usual touristic routine. To immerge in the city, you just have to have a walk through Cartagena’s labyrinth of cobblestones alleys, where huge balconies are wrapped by bugainvilles and massive churches cast their shadows on the tree-lined squares. Take your time and relax in one of the many cafes in Cartagena.

Colon
Colón is the ideal crossroads for a walk through the rainforest or a close look at the Panama Canal. Colón lies at the heart of the country's rich history and innovation. This important port city is less than an hour from Panama's most famous attractions, so it is easy to visit sites such as the Panama railway, Gatun and the old Spanish fortress Fort San Lorenzo. There, everything is graced by the crystal-clear waters and white sand that are always a sweet setting for an unforgettable holiday.Capital of the province of Colón on the Caribbean coast of Panama, Colón is located in the heart of the rich history of the country and its innovation. This important port city is less than an hour from Panama's most famous attractions, so it's easy to visit sites such as the Panama Railroad, Gatun and the old Spanish fortress Fort San Lorenzo. All embellished naturally by crystal clear waters and white sand which always represent a very popular sweet frame for an unforgettable vacation.

Panama Canal

Puntarenas
Pacific Adventures from Puntarenas!Set sail on an exhilarating cruise from Puntarenas, Costa Rica, a vibrant port city on the Pacific coast. Known for its beautiful beaches, lush rainforests, and diverse wildlife, Puntarenas offers an incredible starting point for exploring the natural wonders of Central America and beyond. Prepare for a journey filled with adventure, relaxation, and unforgettable discoveries in one of the world's most biodiverse regions.

Cabo San Lucas

San Diego
San Diego: Sun, Culture and Sea in Southern CaliforniaDuring a stop in San Diego, you can enjoy a perfect mix of culture, nature and relaxation in one of the most vibrant cities in California. Start your exploration from the historic Gaslamp quarter, famous for its Victorian architecture and numerous restaurants and boutiques, ideal for an immersive walk in the heart of the city. Visit Balboa Park, a green oasis with museums, gardens and the famous San Diego Zoo, one of the most renowned in the world for the variety of species and environments. If you love the sea, the Maritime Museum and the USS Midway Museum offer an immersion in naval history and the opportunity to board historic ships. Don't miss the iconic beaches like Coronado Beach or La Jolla, perfect for some relaxation under the sun. San Diego is a must for those looking for culture, fun and breathtaking landscapes.
San Diego: A Historical MosaicSan Diego, known as the birthplace of California, is steeped in rich history, from its early Native American roots to its founding by Spanish missionaries in 1769. The city has evolved from a humble mission into a bustling metropolis, all while preserving its historical charm, evident in the preserved Spanish architecture of Old Town San Diego State Historic Park. This area, along with the Cabrillo National Monument, offers a glimpse into the city's past, showcasing the diverse cultures that have shaped San Diego into the vibrant city it is today.
The Alluring Climate of San DiegoSan Diego's climate is arguably one of its most attractive features, boasting year-round sunshine and mild temperatures. This idyllic weather facilitates an outdoor lifestyle, encouraging visitors to explore the city's expansive beaches, lush parks, and scenic walking paths. Whether you're sunbathing at La Jolla Cove, hiking in Torrey Pines State Natural Reserve, or enjoying waterfront dining, San Diego's climate makes every activity more enjoyable, earning it the title of "America's Finest City."
Discovering San Diego's AttractionsSan Diego's attractions cater to every interest, making it a versatile destination for all types of travelers. The world-renowned San Diego Zoo and Safari Park offer up-close animal encounters, while Balboa Park houses museums, gardens, and the iconic California Tower. For maritime enthusiasts, the USS Midway Museum and the Maritime Museum of San Diego provide insight into naval history. San Diego's proximity to the Mexican border also introduces a unique cultural blend, enriching the city's already diverse array of attractions and activities.
A Taste of San Diego's Culinary DelightsThe culinary scene in San Diego is as vibrant and varied as its landscape, with an emphasis on fresh, local ingredients and seafood. The city is renowned for its fish tacos, a local delicacy that reflects its coastal and Mexican influences. Craft beer enthusiasts will also find a haven here, as San Diego boasts one of the most dynamic craft beer scenes in the country. From upscale dining in the Gaslamp Quarter to casual beachside eateries, San Diego offers a culinary adventure for every palate.
Embarking on a Cruise from San DiegoFor those looking to explore beyond the city, San Diego serves as an ideal departure point for cruises. The city's cruise terminal, located downtown near the vibrant Embarcadero, offers voyages to the Mexican Riviera, Hawaii, and the Panama Canal. Starting your cruise in San Diego not only provides an opportunity to enjoy the city's many attractions but also offers a seamless transition to the relaxation and adventure of a cruise vacation. With its stunning scenery, rich history, and welcoming climate, San Diego is the perfect port of call for cruisers seeking a memorable start to their journey.

Los Angeles
Hollywood to High Seas from Los Angeles!Set sail on an incredible cruise from Los Angeles, California, the vibrant heart of the entertainment industry and a major West Coast port. From the glitz of Hollywood to the sun-kissed beaches, LA offers an exciting departure point for exploring the Mexican Riviera, Alaska, and beyond. Experience the Californian dream before embarking on a journey filled with relaxation, adventure, and unforgettable moments at sea.
Los Angeles: The City of Dreams and OpportunitiesLos Angeles, the city of angels, is an iconic destination that fascinates millions of visitors every year. Located on the west coast of the United States, this vibrant metropolis is known worldwide for its glamorous lifestyle, its film industry and its extraordinary natural beauty.
When to Visit Los Angeles: Climate and SeasonalityLos Angeles enjoys a Mediterranean climate, with hot, dry summers and mild winters. The best time to visit the city is undoubtedly spring and autumn, when the temperatures are pleasant and the days are sunny. In summer, Los Angeles offers numerous outdoor activities, such as walks on the beach and visits to parks, while in winter it is possible to enjoy a more peaceful and relaxed atmosphere.
Unmissable attractions in Los AngelesLos Angeles boasts a vast array of attractions not to be missed. These include Hollywood, with its famous Walk of Fame and Grauman's Chinese Theatre, the Getty Center, an art museum with a breathtaking view of the city, and the Griffith Observatory, from which to admire a spectacular panorama of Los Angeles. Cruisers cannot miss a visit to Santa Monica and Venice Beach, two iconic seaside resorts, and Disneyland Resort, the most famous theme park in the world.
Culinary specialties and typical products of Los AngelesLos Angeles cuisine is a true melting pot of influences, reflecting the cultural diversity of the city. Among the typical dishes, Mexican tacos and burritos stand out, food trucks that offer specialties of all kinds and fusion cuisine restaurants that combine culinary traditions from all over the world. Cruisers will also be able to taste the renowned Californian wines and purchase local artisan products, such as clothing and fashion accessories.
Discover the Best of California on Board a Cruise from Los AngelesLos Angeles is an ideal starting point for a cruise to discover the west coast of the United States and Mexico. Embarking on a cruise that departs from Los Angeles means having the opportunity to visit iconic destinations such as San Francisco, Seattle, Vancouver and Cabo San Lucas, admiring breathtaking landscapes, exploring natural sites and experiencing unique cultural experiences at each stage of the journey. Whether you choose to sail north or south, a cruise from Los Angeles will give you unforgettable memories and will let you discover the best of California and the Pacific.

Seattle
Pacific Northwest Adventures from Seattle!Set sail on an incredible cruise from Seattle, Washington, the vibrant Emerald City of the Pacific Northwest. Known for its iconic Space Needle, bustling Pike Place Market, and stunning natural surroundings, Seattle offers a fantastic departure point for exploring the majestic Alaskan wilderness and the scenic Pacific Coast. Experience its unique blend of urban charm and outdoor adventure before embarking on a journey filled with breathtaking landscapes and unforgettable discoveries at sea.
Discovering Seattle's Historical RootsSeattle, nestled between Puget Sound and Lake Washington, boasts a rich history that dates back to its founding in 1851. Originally inhabited by the Duwamish and Suquamish tribes, the city has grown from a small logging town to a thriving metropolis, known for its pivotal role in the Klondike Gold Rush. This era of prosperity laid the foundation for the city's diverse cultural landscape, further enriched by the influence of Asian, Scandinavian, and Native American communities. The historic Pioneer Square district, with its Renaissance Revival architecture, stands as a testament to Seattle's storied past, inviting visitors to explore its deep historical roots.
Experiencing Seattle's Unique ClimateContrary to popular belief, Seattle's climate is not solely defined by rain. The city enjoys a temperate marine climate, characterized by mild, wet winters and warm, dry summers. This unique weather pattern supports a lush, green environment year-round, earning Seattle the nickname "The Emerald City." The mild climate encourages outdoor activities, from hiking in the nearby Cascades to boating on Puget Sound, making Seattle an ideal destination for nature lovers and adventure seekers alike.
Seattle's Must-Visit AttractionsSeattle's landscape is dotted with iconic attractions that cater to a wide array of interests. The Space Needle, a legacy of the 1962 World's Fair, offers breathtaking views of the city and beyond. Pike Place Market, one of the oldest continuously operated public markets in the United States, provides a taste of local culture and cuisine. For art enthusiasts, the Seattle Art Museum and the Chihuly Garden and Glass exhibit showcase the city's artistic side. Outdoor adventurers will find solace in Discovery Park's expansive trails and beaches. These attractions, among others, make Seattle a vibrant destination for visitors and cruisers alike.
Savoring Seattle's Culinary SceneSeattle's culinary scene is as diverse as its population, with a strong emphasis on fresh, local ingredients. The city's coastal location ensures a steady supply of seafood, with Pacific Northwest salmon and Dungeness crab featured prominently on many menus. Coffee culture is deeply ingrained in Seattle's identity, home to the original Starbucks and a plethora of independent coffee shops. The fusion of Asian, European, and Native American cuisines provides a rich gastronomic landscape, offering everything from gourmet dining to street food delights.
Setting Sail from SeattleAs a premier gateway to the Pacific Northwest and Alaska, Seattle is an ideal starting point for cruises. The city's modern cruise terminals, located along the stunning waterfront, provide easy access to the breathtaking beauty of Alaska, the Canadian Pacific coast, and beyond. Embarking on a cruise from Seattle not only promises an unforgettable voyage but also the opportunity to explore this dynamic city's history, culture, and natural beauty. With special deals and packages available, beginning your journey in Seattle offers a seamless transition from urban exploration to the serene landscapes of the sea.