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Cruises of Royal Caribbean in Panama

  • 2025
  • 2026
  • 2027
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78 cruises

Caribbean: Panama, Colombia, Netherlands Antilles, Aruba

Colon Itinerary Caribbean
from $1,631
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | Oct 11, 2025
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Willemstad,
5. Oranjestad,
6. navigation,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from $1,621
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | Oct 18, 2025
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Oranjestad,
5. Willemstad,
6. navigation,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Netherlands Antilles, Aruba

Colon Itinerary Caribbean
from $1,631
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | Oct 25, 2025
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Willemstad,
5. Oranjestad,
6. navigation,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from $1,510
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | Nov 1, 2025
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Oranjestad,
5. Willemstad,
6. navigation,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Netherlands Antilles

Colon Itinerary Caribbean
from $1,398
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | Nov 8, 2025
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Kralendijk,
5. Willemstad,
6. navigation,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from $1,412
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | Nov 15, 2025
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Oranjestad,
5. Willemstad,
6. navigation,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from $1,403
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | Nov 22, 2025
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. navigation,
5. Oranjestad,
6. Willemstad,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Netherlands Antilles

Colon Itinerary Caribbean
from $1,399
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | Nov 29, 2025
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Kralendijk,
5. Willemstad,
6. navigation,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from $1,277
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | Dec 6, 2025
Duration: 6 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Oranjestad,
5. Willemstad,
6. navigation,
7. Colon

Caribbean: Panama, Colombia, Netherlands Antilles, Aruba

Colon Itinerary Caribbean
from $1,644
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | Dec 12, 2025
Duration: 8 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. navigation,
3. Cartagena De Indias,
4. navigation,
5. Kralendijk,
6. Oranjestad,
7. Willemstad,
8. navigation,
9. Colon

Caribbean: Panama, Colombia, Netherlands Antilles, Aruba

Colon Itinerary Caribbean
from $1,434
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | Dec 20, 2025
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. navigation,
5. Willemstad,
6. Oranjestad,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from $1,946
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | Dec 27, 2025
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Oranjestad,
5. Kralendijk,
6. navigation,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Netherlands Antilles, Aruba

Colon Itinerary Caribbean
from $1,178
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | Jan 3, 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. navigation,
5. Kralendijk,
6. Oranjestad,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from $1,345
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | Jan 10, 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Oranjestad,
5. navigation,
6. Willemstad,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Netherlands Antilles, Aruba

Colon Itinerary Caribbean
from $1,367
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | Jan 17, 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Kralendijk,
5. Oranjestad,
6. navigation,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from $1,256
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | Jan 24, 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Oranjestad,
5. Kralendijk,
6. navigation,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from $1,252
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | Jan 31, 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Oranjestad,
5. Kralendijk,
6. navigation,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from $1,132
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | Feb 7, 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Oranjestad,
5. Kralendijk,
6. navigation,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from $1,253
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | Feb 14, 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. navigation,
5. Oranjestad,
6. Willemstad,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Netherlands Antilles, Aruba

Colon Itinerary Caribbean
from $1,081
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | Feb 21, 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. navigation,
5. Kralendijk,
6. Oranjestad,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Netherlands Antilles, Aruba

Colon Itinerary Caribbean
from $1,130
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | Feb 28, 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. navigation,
5. Kralendijk,
6. Oranjestad,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from $1,130
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | Mar 7, 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Oranjestad,
5. navigation,
6. Willemstad,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Netherlands Antilles, Aruba

Colon Itinerary Caribbean
from $1,128
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | Mar 14, 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Willemstad,
5. Oranjestad,
6. navigation,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from $1,128
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | Mar 21, 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. navigation,
5. Oranjestad,
6. Willemstad,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from $1,454
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | Mar 28, 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. navigation,
5. Oranjestad,
6. Kralendijk,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from $1,296
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | Apr 4, 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. navigation,
5. Oranjestad,
6. Willemstad,
7. navigation,
8. Colon

Caribbean: Panama, Colombia, Netherlands Antilles, Aruba

Colon Itinerary Caribbean
from $1,298
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | Apr 11, 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Willemstad,
5. Oranjestad,
6. navigation,
7. navigation,
8. Colon
sold out

Panama, Colombia, Netherlands Antilles, Aruba

Colon Itinerary Caribbean
from $1,013
price per person Taxes included
Serenade Of The Seas | Apr 18, 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Willemstad,
5. Oranjestad,
6. navigation,
7. navigation,
8. Colon

Central America: Panama, Costa Rica, Mexico, United States

Colon Itinerary Central America
from $1,478
price per person Taxes included
See the cruise Book Online Book Online
Serenade Of The Seas | Apr 25, 2026
Duration: 10 nights
Departure from: Colon Landing: Los Angeles
Itinerary:
1. Colon,
2. navigation,
3. navigation,
4. Puntarenas,
5. navigation,
6. Huatulco,
7. navigation,
8. Puerto Vallarta,
9. navigation,
10. navigation,
11. Los Angeles

Caribbean: Panama, Colombia, Aruba, Netherlands Antilles

Colon Itinerary Caribbean
from $1,126
price per person Taxes included
See the cruise Book Online Book Online
Jewel Of The Seas | May 9, 2026
Duration: 7 nights
Departure from: Colon Landing: Colon
Itinerary:
1. Colon,
2. Cartagena De Indias,
3. navigation,
4. Oranjestad,
5. Willemstad,
6. navigation,
7. navigation,
8. Colon
78 cruises