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Cruises from Santo Domingo

Caribbean Rhythms from Santo Domingo!

Embark on a vibrant Caribbean cruise from Santo Domingo, the historic capital of the Dominican Republic. As the oldest continuously inhabited European-established settlement in the Americas, this city offers an unparalleled blend of colonial charm and lively Caribbean culture. Explore its UNESCO-listed Colonial Zone before setting sail on a journey filled with sun-drenched beaches, rhythmic music, and unforgettable island discoveries.

28 cruises
Caribbean: Dominican Republic, Martinique, Guadeloupe, Saint Kitts and Nevis, British Virgin Islands
Santo Domingo Itinerary Caribbean
from $459
price per person Taxes included
See the cruise Book Online Book Online
Costa Favolosa | Dec 14, 2026
Duration: 7 nights
Departure from: Santo Domingo Landing: Santo Domingo
Itinerary:
1. Santo Domingo,
2. navigation,
3. Fort de france,
4. Pointe à Pitre,
5. Basseterre,
6. Tortola Island,
7. Catalina Island,
8. Santo Domingo
Caribbean: Dominican Republic, Martinique, Guadeloupe, Saint Kitts and Nevis, Antigua and Barbuda, British Virgin Islands
Santo Domingo Itinerary Caribbean
from $581
price per person Taxes included
See the cruise Book Online Book Online
Costa Favolosa | Dec 7, 2026
Duration: 7 nights
Departure from: Santo Domingo Landing: Santo Domingo
Itinerary:
1. Santo Domingo,
2. navigation,
3. Fort de france,
4. Pointe à Pitre,
5. Basseterre,
6. Saint Johns,
7. Tortola Island,
8. Santo Domingo
Caribbean: Dominican Republic, Guadeloupe, Martinique, Saint Kitts and Nevis, Antigua and Barbuda, British Virgin Islands
Santo Domingo Itinerary Caribbean
from $593
price per person Taxes included
See the cruise Book Online Book Online
Costa Favolosa | Nov 30, 2026
Duration: 7 nights
Departure from: Santo Domingo Landing: Santo Domingo
Itinerary:
1. Santo Domingo,
2. navigation,
3. Pointe à Pitre,
4. Fort de france,
5. Basseterre,
6. Saint Johns,
7. Tortola Island,
8. Santo Domingo
Caribbean: Dominican Republic, Antigua and Barbuda, Martinique, Guadeloupe, Saint Kitts and Nevis, Sint Maarten
Santo Domingo Itinerary Caribbean
from $617
price per person Taxes included
See the cruise Book Online Book Online
Costa Favolosa | Jan 18, 2027
Duration: 7 nights
Departure from: Santo Domingo Landing: Santo Domingo
Itinerary:
1. Santo Domingo,
2. navigation,
3. Saint Johns,
4. Fort de france,
5. Pointe à Pitre,
6. Basseterre,
7. Sint Maarten,
8. Santo Domingo
Caribbean: Dominican Republic, Dominica, Martinique, Guadeloupe, Saint Kitts and Nevis, British Virgin Islands
Santo Domingo Itinerary Caribbean
from $617
price per person Taxes included
See the cruise Book Online Book Online
Costa Favolosa | Jan 25, 2027
Duration: 7 nights
Departure from: Santo Domingo Landing: Santo Domingo
Itinerary:
1. Santo Domingo,
2. navigation,
3. Roseau,
4. Fort de france,
5. Pointe à Pitre,
6. Basseterre,
7. Tortola Island,
8. Santo Domingo
28 cruises

Departure calendar Santo Domingo

Browse the catalog of all cruises departing from Santo Domingo now and find the one that suits your needs best.

  • 2026
  • 2027
December 2025
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All ships departing from Santo Domingo

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Costa Fascinosa Images of Costa Fascinosa Costa Favolosa Images of Costa Favolosa